byte 1 is the first bioprinter with integrated inline characterization. Embedded sensors monitor material properties in real time, so your tissue model is printed as intended, every time.
Reliable tissue models start with reproducible prints. Yet the same protocol can produce different results from one lab to the next.
12 labs.
Same protocol.
12 different results.
“…the product equivalency between locations could not be shown.” A round-robin study published in 2023 compared extrusion-based printing across 12 German academic labs using centrally supplied materials and standardized procedures. The authors found that operators and differences in printing equipment limited comparability, and called for greater process control and automation.
Source: 2023 round-robin study · PubMed 37769669Three systemic problems are costing your lab months of work, and no current device addresses them.
To understand the bioink you must rely on external measurement devices, then hope the results transfer to the printer. Temperature-sensitive bioinks are especially intricate, and no system on the market enables characterization during the actual printing process.
Conventional systems can only alternate between materials: hard transitions, no gradients. Each material needs its own pre-filled cartridge, wasting expensive bioinks and multiplying preparation errors. You get discrete switches, never biological or mechanical gradients.
You set parameters and hope. As bioink viscosity shifts mid-print there's no system to detect it. You find out 14 days of culture later, once the experiment has already failed. Untracked mechanical stresses turn well-plate data into random datasets.
byte 1 combines four integrated solutions to make reproducibility the default, not the exception.
Print 100+ material combinations, versus 6 with competitors. Any cell type. Any bioink. In one session.
Integrated sensors characterize material properties and detect rheological shifts in real time during printing. Know exactly what your bioink is doing before it affects your construct.
The only system on the market with seamless temperature control across the full biological range: 4 °C to 50 °C. Run cold collagen next to warm GelMA, simultaneously.
All sensor data from the three systems above feeds a unified automation and feedback engine. byte 1 independently handles print jobs, identifies issues, and self-corrects based on pre-characterizations. The protocol lives in the machine, not in your most experienced student's head.
Set it. Print it. Trust it.
byte 1 supports a broad range of bioprinting applications, from tissue model research to bioink development and preclinical studies.
Develop tissue models faster and more efficiently with transparent datasets for each model, helping shorten time to publication or market.
Characterize new formulations directly in the printer. Inline sensing tracks how your bioink behaves, turning recipe work into measured data instead of trial and error.
Produce reproducible 3D human tissue models for compound screening, toxicity work and preclinical studies.
PD. Dr. rer. nat. Rafael Schmid
University Hospital Erlangen
"Our breast cancer and melanoma research relies on recreating the tumor microenvironment, printing multiple materials at precisely controlled temperatures. With the RevoBITs multimaterial printhead and continuous thermal regulation, we can model the microenvironment in far greater detail than other systems allow, and significantly accelerate our work."
Jun.-Prof. Dr. Tomasz Jüngst
University of Würzburg
"RevoBITs technology will change bioprinting! Precise process control combined with multi-material printing create the foundation for more realistic tissue models and will accelerate the path to new therapies."
PD. Dr. rer. nat. Natascha Schäfer
University Hospital Würzburg
"RevoBITs provides the solutions we need, enabling the precise 3D printing of nerve tissue models using intelligently mixed bioinks."
A team of Hardware, Software, Electronics, Material and Tissue Engineers. We build the machine according to the biological needs.
